While purchasing a bioreactor for CHO, HeLa, HEK-293 and other cell lines consider gentle mixing, smallest volume possible, sterility, ideal gas mix, efficient gas exchange, exchangeable vessel volume at low cost, peristaltic pumps for long runs and precise temperature control.
Up and down agitation with 'fish-tail' discs provides gentle (minimal shear stress) and efficient mixing (perfect gas and mass exchange).
Ideal gas supply to cell culture varies with temperature & media supplements.Switch to automatic & reliable MINI-4-GAS gas mixing module.
Submerged aeration in cell culture needs an efficient sparger which is not blocked by deposits. Self-cleaning microsparger of MINIFOR bioreactor for long runs (for e.g. months) with efficient sparging.
It is important to have a precise temperature control without overheating. IR heater in MINIFOR bioreactor with automatic volume recognition allows precise temperature control.
LAMBDA peristaltic pumps are specially developed for long term continuous cell cultures with reduced pulsation and stable flow rates.
Vessel volumes could be exchanged from 35 ml to over 6 L for downstream processing in a single MINIFOR bioreactor unit.